Re: Statins
Originally Posted by
Wrinkly
->
Ted I don't need another lecture from you, I have had the values of statins explained from my GP.
As I have said to you many times before, We are all different, what suits one might not suit another.
It may be true that we are all different but the way the human body produces cholesterol is the same for all humans.
It is simply a matter of fact that if you dam a stream to block the flow that will inevitably affect everything DOWNSTREAM of the DAM.
So with the effect of statins that dam the cholesterol metabolic pathway some way UPSTREAM if you look at the diagram here.
I've already mentioned the fact that the Ubiqinones include CoQ10 that will if the statin dam is effective also be less than required so supplementation should be implemented for everyone on statins.
My main concern is the effect on 7 dehydrocholesterol which is the precusor molecule for cholesterol and also for Cholecalciferol which I'm sure you know is Vitamin D3 so EVERY HUMAN taking statins to reduce cholesterol will INEVITABLY have a lower potential for creating Vitamin D3 and should be supplementing with effective amounts.
So why ask for trouble when you can easily avoid it?
If you look at what happens after cholesterol is produced you will see one of those arrows pointing to STEROID HORMONES. One of which is Testosterone.
If you think I'm making this up you can download this power point slideshow explaining the process of
[PPT] Synthesis of Steroid Hormones including Testosterone.
Now it sure doesn't bother me if you retain your sexual functioning or not.
Dr Briffa explains more here
Can statins impair sexual functioning in men?
As we know for certain statins block the mevalonate pathway upstream of CoQ10, 7 dehydrocholesterol (vitamin D) and so reduce cholesterol production which is required for the production of steroid hormones one of which is TESTOSTERONE, we know for certain that if it reduces cholesterol it must also reduce the ability to produce testosterone that is made from cholesterol.
Your choice of course but I'd rather preserve my manhood and my life for as long as possible.
We can see from the way statins work that both Vitamin D production and testosterone production must inevitably be lowered if cholestolerol is lowered.
Does it matter if you have low vitamin D and low testosterone?
Look at this
Combination of low free testosterone and low vitamin D predicts mortality in older men referred for coronary angiography.
You can choose to be a victim or not as you want.
Effect of vitamin D supplementation on testosterone levels in men.
So if you use a reasonable amount of Vitamin D3 (at least 5000iu for the UK (the above research was Austria nearer the sun) you will obtain a significant increase in total testosterone levels.
I bet your doctor didn't explain that to you.