19-11-2020, 10:35 AM
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Covid: Oxford vaccine shows 'encouraging' immune response in older adults
https://www.bbc.co.uk/news/health-54993652They are also testing whether the vaccine stops people developing Covid-19 in larger, phase three trials.
Early results from this crucial stage are expected in the coming weeks.
The UK has already ordered 100 million doses of the Oxford vaccine, manufactured by AstraZeneca.
Older people's weaker immune systems mean vaccines do not tend to function as well as they do in younger people.
These trial results from the University of Oxford, peer-reviewed in the Lancet, suggest that may not be a problem.
They show that older adults aged 56-69 and over 70 had a similar immune response to younger adults aged 18-55.
23-11-2020, 11:03 AM
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Re: Covid: Oxford vaccine shows 'encouraging' immune response in older adults
Covid-19: Oxford University vaccine shows 70% protectionhttps://www.bbc.co.uk/news/health-55040635
It will be seen as a triumph, but also comes off the back of Pfizer and Moderna showing 95% protection. However, the Oxford jab is far cheaper, and is easier to store and get to every corner of the world than the other two. There is also intriguing data that suggests perfecting the dose could increase protection up to 90%.
The vaccine has been developed in around 10 months, a process that normally takes a decade.
23-11-2020, 01:42 PM
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Re: Covid: Oxford vaccine shows 'encouraging' immune response in older adults
Oxford vaccine: How did they make it so quickly?https://www.bbc.co.uk/news/health-55041371
They are two statements that sound like a contradiction, and have led some to ask how we can be sure the Oxford vaccine - which has published its first results showing it is highly effective at stopping Covid-19 - is safe when it has been made so fast.
So, this is the real story of how the Oxford vaccine happened so quickly.
It is one that relies on good fortune as well as scientific brilliance; has origins in both a deadly Ebola outbreak and a chimpanzee's runny nose; and sees the researchers go from having no money in the bank to chartering private planes.
The phases:
- The work started years ago
- The critical piece of technology
- January 1
- A lucky break
- Money, money, money
- Unglamorous, but vital checks
- Back-to-back trials
27-11-2020, 08:04 PM
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Re: Covid: Oxford vaccine shows 'encouraging' immune response in older adults
Oxford Covid vaccine: Regulator asked to assess jabhttps://www.bbc.co.uk/news/uk-55096434
The referral to the Medicines and Healthcare products Regulatory Agency (MHRA) marked "a significant first step" in getting the vaccine "approved for deployment", the government said.
It follows news that the jab was "highly effective" in advanced trials.
The UK government has pre-ordered 100m doses of the Oxford vaccine.
The government's latest request to the MHRA comes a week after the regulator was asked to assess the Pfizer/BioNTech vaccine.
30-11-2020, 03:58 AM
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Re: Covid: Oxford vaccine shows 'encouraging' immune response in older adults
A very interesting podcast about the Oxford Vaccine and why serious questions have been asked about the vaccine.Last week, AstraZeneca reported a 90 percent efficacy rate for its vaccine - but also another lower rate for another part of the trial.
Now questions are emerging around how the trial was run, and if parts of it were accidental or if they were on purpose.
https://abcmedia.akamaized.net/news/..._questions.mp3
Definitely worth a listen - information from real experts
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