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A Neanderthal could easily pass as a modern man. On this programme they had an actor made up as one complete with prosthetics to extend his forehead and jawline, put him in a posh suit and had him ride up and down on the subway. No-one battered and eye.
Was it filmed in London? If so, he'd be just another "strange" face amongst millions of "strange" faces from all over the world:
At the 2011 census, London had a population of 8,173,941. Of this number, 44.9% were White British. 37% of the population were born outside the UK, including 24.5% born outside of Europe.